GABBR2 anticorps (pSer783) (AbBy Fluor® 750)
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- Antigène Voir toutes GABBR2 Anticorps
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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Épitope
- pSer783
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GABBR2 est conjugé à/à la AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser783
- Isotype
- IgG
- Top Product
- Discover our top product GABBR2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
- Autre désignation
- GABBR2 (GABBR2 Produits)
- Synonymes
- anticorps Gpr51, anticorps GABABR2, anticorps GPR51, anticorps GPRC3B, anticorps HG20, anticorps HRIHFB2099, anticorps Gb2, anticorps Gm425, anticorps GABA(B)R2, anticorps si:dkey-190l1.2, anticorps gamma-aminobutyric acid type B receptor subunit 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog, anticorps GABBR2, anticorps LOC100448699, anticorps gabbr2, anticorps Gabbr2, anticorps gabbr2.S
- Sujet
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Synonyms: GABA B Receptor 2 phospho S783, p-GABA B Receptor 2 phospho S783, GABBR2 Ser783, p-GABBR2 Ser783, GABBR2, GB2, G protein coupled receptor 51, G-protein coupled receptor 51, GAB B R2, GABA B R2, GABA B receptor 2, GABA B RECEPTOR, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABA[[B]]R2, GABAB R2, GABABR 2, GABABR2, GABB R2, GABBR 2, Gabbr2, GABR2_HUMAN, Gamma aminobutyric acid GABA B receptor 2, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb2, GH07312, GPR 51, GPR51, GPRC 3B, GPRC3B, HG 20, HG20, HRIHFB2099, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, BcDNA:GH07312, CG6706, CT20836, D GABA[[B]]R2, D Gaba2, FLJ36928.
Background: Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
- ID gène
- 9568
- Pathways
- cAMP Metabolic Process
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