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Nanos Homolog 1 anticorps (N-Term)

NANOS1 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500316
  • Antigène Voir toutes Nanos Homolog 1 (NANOS1) Anticorps
    Nanos Homolog 1 (NANOS1)
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 12
    • 6
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 41
    • 1
    • 1
    Lapin
    Clonalité
    • 42
    • 1
    Polyclonal
    Conjugué
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nanos Homolog 1 est non-conjugé
    Application
    • 30
    • 22
    • 17
    • 7
    • 6
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects NANOS1 at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogène
    Nanos1 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Nanos1.
    Isotype
    IgG
    Top Product
    Discover our top product NANOS1 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Nanos Homolog 1 (NANOS1)
    Autre désignation
    NANOS1 (NANOS1 Produits)
    Synonymes
    anticorps NOS1, anticorps nanos1, anticorps fb76c12, anticorps wu:fb93h11, anticorps wu:fb98e07, anticorps wu:fq21a10, anticorps Xcat-2, anticorps nos1, anticorps xnos1, anticorps xcat-2, anticorps LOC100144352, anticorps NANOS1A, anticorps nanos C2HC-type zinc finger 1, anticorps nanos homolog 1, anticorps nanos homolog 1 (Drosophila), anticorps nanos homolog 1 L homeolog, anticorps Nanos homolog 1, anticorps nanos1, anticorps NANOS1, anticorps nanos1, anticorps Nanos1, anticorps nanos1.L, anticorps nano1, anticorps nanos1a
    Sujet
    Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos. Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain. Interestingly, unlike mice deficient in either nanos2 or nanos3, mice lacking the nanos1 gene develop normally with no sign of abnormalities. Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn. Furthermore, overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion, allowing the cancer cells to develop strong migratory and invasive properties. These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors.Synonyms: NOS1, Nanos homolog 1
    ID gène
    340719
    UniProt
    Q8WY41
    Pathways
    Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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