NRN1 anticorps (Center)

N° du produit ABIN500332

Détail du produit anti-NRN1 anticorps

Antigène: NRN1 (Neuritin 1 (NRN1))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Neuritin.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: Neuritin antibody was raised against a 20 amino acid peptide from near the center of human neuritin.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur NRN1

Antigène: NRN1 (Neuritin 1 (NRN1))

Autre désignation: Neuritin (NRN1 Produits)

Synonymes: anticorps NRN, anticorps dJ380B8.2, anticorps 0710008J23Rik, anticorps Cpg15, anticorps Nrn, anticorps neuritin, anticorps nrn1, anticorps zgc:92828, anticorps NRN1, anticorps cpg15, anticorps nrn, anticorps nrn1-a, anticorps nrn1-b, anticorps nrn1b, anticorps neuritin 1, anticorps neuritin 1a, anticorps neuritin 1 S homeolog, anticorps neuritin 1 L homeolog, anticorps NRN1, anticorps Nrn1, anticorps nrn1a, anticorps nrn1, anticorps nrn1.S, anticorps nrn1.L

Sujet: As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.Synonyms: NRN, NRN1

ID gène: 51299

NCBI Accession: NP_057672

UniProt: Q9NPD7