G6PC2 anticorps (AbBy Fluor® 680)

N° du produit ABIN5003594

Détail du produit anti-G6PC2 anticorps (AbBy Fluor® 680)

Antigène: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp G6PC2 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur G6PC2

Antigène: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Autre désignation: Glucose 6 phosphatase 2/ IGRP (G6PC2 Produits)

Synonymes: anticorps IGRP, anticorps G6pc-rs, anticorps Igrp, anticorps g6pc2, anticorps igrp, anticorps glucose-6-phosphatase catalytic subunit 2, anticorps glucose-6-phosphatase, catalytic, 2, anticorps glucose-6-phosphatase, catalytic, 2 S homeolog, anticorps G6PC2, anticorps G6pc2, anticorps g6pc2.S

Sujet:

Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

ID gène: 57818