GPR37L1 anticorps (AA 101-200) (AbBy Fluor® 750)
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- Antigène Voir toutes GPR37L1 Anticorps
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
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Épitope
- AA 101-200
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GPR37L1 est conjugé à/à la AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GPR37L1
- Isotype
- IgG
- Top Product
- Discover our top product GPR37L1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
- Autre désignation
- GPR37L1 (GPR37L1 Produits)
- Synonymes
- anticorps GPR37L1, anticorps ET(B)R-LP-2, anticorps ETBR-LP-2, anticorps AW047233, anticorps CAG-18, anticorps D0Kist8, anticorps G protein-coupled receptor 37 like 1, anticorps G protein-coupled receptor 37-like 1, anticorps GPR37L1, anticorps Gpr37l1
- Sujet
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Synonyms: Endothelin B receptor-like protein 2, ET(B)R-LP-2, ETBR-LP-2, ETBR2, ETBRLP2, G-protein coupled receptor 37-like 1, GPR37L1, ETBR2_HUMAN.
Background: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
- ID gène
- 9283
- UniProt
- O60883
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