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HHCM anticorps (AA 301-400) (AbBy Fluor® 750)

HHCM Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN5004584
  • Antigène Tous les produits HHCM
    HHCM (Mahlavu Hepatocellular Carcinoma (HHCM))
    Épitope
    • 14
    • 11
    • 7
    • 1
    AA 301-400
    Reactivité
    Humain
    Hôte
    • 26
    Lapin
    Clonalité
    • 26
    Polyclonal
    Conjugué
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HHCM est conjugé à/à la AbBy Fluor® 750
    Application
    • 26
    • 14
    • 12
    • 12
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HHCM
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HHCM (Mahlavu Hepatocellular Carcinoma (HHCM))
    Autre désignation
    HHCM (HHCM Produits)
    Synonymes
    anticorps hhc(M), anticorps Mahlavu hepatocellular carcinoma, anticorps HHCM
    Sujet

    Synonyms: Hepatocellular carcinoma protein HHCM, HHCM, Mahlavu hepatocellular carcinoma, HHCM_HUMAN.

    Background: HHCM is a 467 amino acid protein that has oncogenic transforming capabilities on a variety of different cell lines. When HHCM was transfected into BRL-1 (Buffalo rat liver) or NIH3T3 cells, the cells exhibited significant morphological changes, anchorage independent growth and loss of contact inhibition. When the cells were inoculated into rats and mice, they became highly tumorigenic. HHCM gene-related DNA sequences were found in at least nineteen hepatomas of Asian origin. The gene encoding HHCM maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis.

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