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PDCD5 anticorps (N-Term)

PDCD5 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500465
  • Antigène Voir toutes PDCD5 Anticorps
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 52
    • 2
    Lapin
    Clonalité
    • 52
    • 1
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDCD5 est non-conjugé
    Application
    • 38
    • 21
    • 13
    • 13
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects PDCD5 at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    PDCD5 antibody was raised against a 13 amino acid peptide from near the amino terminus of human PDCD5.
    Isotype
    IgG
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    Discover our top product PDCD5 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    Autre désignation
    PDCD5 (PDCD5 Produits)
    Synonymes
    anticorps zgc:56315, anticorps tfar19, anticorps DKFZp468P187, anticorps TFAR19, anticorps 2200003D22Rik, anticorps AA408513, anticorps Tfar19, anticorps programmed cell death 5, anticorps programmed cell death 5 S homeolog, anticorps DNA-binding protein, anticorps pdcd5, anticorps PDCD5, anticorps pdcd5.S, anticorps SSO_RS01750, anticorps Pdcd5
    Sujet
    Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis (5). The nucleotide polymorphisms in the 5?-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.Synonyms: Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19
    ID gène
    9141
    NCBI Accession
    NP_004699
    UniProt
    O14737
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