PLXDC2 anticorps (N-Term)

N° du produit ABIN500515

Détail du produit anti-PLXDC2 anticorps

Antigène: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLXDC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Plxdc2 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Plxdc2 antibody was raised against a 18 amino acid peptide from near the amino terminus of human Plxdc2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur PLXDC2

Antigène: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Autre désignation: PLXDC2 / TEM7R (PLXDC2 Produits)

Synonymes: anticorps MGC79122, anticorps TEM7R, anticorps 1200007L24Rik, anticorps 5430431D22Rik, anticorps AI646728, anticorps AU022916, anticorps AV231634, anticorps Tem7r, anticorps plexin domain containing 2, anticorps plexin domain containing 2 L homeolog, anticorps PLXDC2, anticorps plxdc2.L, anticorps plxdc2, anticorps Plxdc2

Sujet: Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57 % amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.Synonyms: Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein

ID gène: 84898

UniProt: Q6UX71