PPPDE1 anticorps (C-Term)

N° du produit ABIN500519

Détail du produit anti-PPPDE1 anticorps

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPPDE1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PNAS4.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinty chromatography

Immunogène: PNAS4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PNAS4.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur PPPDE1

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Autre désignation: PPPDE1 (PPPDE1 Produits)

Synonymes: anticorps PPPDE1, anticorps FAM152A, anticorps 5830417C01Rik, anticorps DeSI-2, anticorps Fam152a, anticorps Pppde1, anticorps DKFZp459O172, anticorps C1orf121, anticorps DESI, anticorps DESI1, anticorps PNAS-4, anticorps CGI-146, anticorps fam152a, anticorps pnas4, anticorps pppde1, anticorps cb238, anticorps desi1, anticorps sb:cb238, anticorps wu:fi12d12, anticorps zgc:100860, anticorps desumoylating isopeptidase 2, anticorps desumoylating isopeptidase 2 L homeolog, anticorps DESI2, anticorps Desi2, anticorps desi2.L, anticorps desi2

Sujet: PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.Synonyms: C1orf121, CGI-146, FAM152A, PNAS-4, PNAS4, PPPDE peptidase domain-containing protein 1

ID gène: 51029

NCBI Accession: NP_057160

UniProt: Q9BSY9