TBKBP1 anticorps (C-Term)

N° du produit ABIN500543

Détail du produit anti-TBKBP1 anticorps

Antigène: TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBKBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Prosapip2.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Prosapip2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TBKBP1

Antigène: TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

Autre désignation: TBKBP1 (TBKBP1 Produits)

Synonymes: anticorps TBKBP1, anticorps ProSAPiP2, anticorps SINTBAD, anticorps 3110043L15Rik, anticorps Prosapip2, anticorps TBK1 binding protein 1, anticorps TBKBP1, anticorps Tbkbp1

Sujet: Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.Synonyms: KIAA0775, ProSAPiP2, Sintbad, TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1

ID gène: 9755

NCBI Accession: NP_055541

UniProt: A7MCY6

Pathways: SARS-CoV-2 Protein Interactome