KDM5B anticorps (AA 65-165) (AbBy Fluor® 750)
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- Antigène Voir toutes KDM5B Anticorps
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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Épitope
- AA 65-165
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDM5B est conjugé à/à la AbBy Fluor® 750
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
- Isotype
- IgG
- Top Product
- Discover our top product KDM5B Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
- Autre désignation
- KDM5B (KDM5B Produits)
- Synonymes
- anticorps jarid1b, anticorps jarid1ba, anticorps id:ibd5050, anticorps wu:fd15c05, anticorps cb264, anticorps jarid1bb, anticorps plu1, anticorps wu:fc44h11, anticorps zgc:85741, anticorps JARID1B, anticorps CT31, anticorps PLU-1, anticorps PLU1, anticorps PUT1, anticorps RBBP2H1A, anticorps 2010009J12Rik, anticorps 2210016I17Rik, anticorps AW556288, anticorps D1Ertd202e, anticorps Jarid1b, anticorps Plu1, anticorps Rb-Bp2, anticorps mKIAA4034, anticorps RGD1565602, anticorps lysine (K)-specific demethylase 5Ba, anticorps lysine (K)-specific demethylase 5Bb, anticorps lysine demethylase 5B, anticorps lysine (K)-specific demethylase 5B, anticorps kdm5ba, anticorps kdm5bb, anticorps KDM5B, anticorps Kdm5b
- Sujet
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Synonyms: CT31, PLU1, PUT1, PLU-1, JARID1B, PPP1R98, RBBP2H1A, Lysine-specific demethylase 5B, Cancer/testis antigen 31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1, KDM5B, RBBP2H1
Background: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
- ID gène
- 10765
- UniProt
- Q9UGL1
- Pathways
- L'effet Warburg
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