KCNJ11 anticorps (pThr224) (AbBy Fluor® 680)
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- Antigène Voir toutes KCNJ11 Anticorps
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
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Épitope
- pThr224
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KCNJ11 est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Kir6.2 around the phosphorylation site of Thr224
- Isotype
- IgG
- Top Product
- Discover our top product KCNJ11 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- Autre désignation
- Kir6.2 (KCNJ11 Produits)
- Synonymes
- anticorps kir6.2, anticorps Kir6.2, anticorps mBIR, anticorps BIR, anticorps HHF2, anticorps IKATP, anticorps KIR6.2, anticorps PHHI, anticorps TNDM3, anticorps potassium voltage-gated channel subfamily J member 11, anticorps potassium inwardly-rectifying channel, subfamily J, member 11, anticorps potassium inwardly rectifying channel, subfamily J, member 11, anticorps KCNJ11, anticorps kcnj11, anticorps Kcnj11
- Sujet
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Synonyms: p-Kir6.2 phospho T224, ATP sensitive inward rectier potassium channel 11, Beta cell inward rectier subunit, mBIR, BIR, HHF 2, HHF2, IKATP, Inward rectier K+ channel Kir6.2, Inwardly rectying potassium channel KIR6.2, IRK 11, IRK11, KCNJ11, Kir 6.2, Kir6.2, MGC133230, PHHI, Potassium channel, inwardly rectying subfamily J member 11, Potassium inwardly rectying channel J11, TNDM 3, TNDM3.
Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
- Pathways
- Negative Regulation of Hormone Secretion
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