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RHBDD1 anticorps (C-Term)

RHBDD1 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500589
  • Antigène Voir toutes RHBDD1 Anticorps
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    Épitope
    • 2
    • 1
    C-Term
    Reactivité
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 6
    Lapin
    Clonalité
    • 6
    Polyclonal
    Conjugué
    • 6
    Cet anticorp RHBDD1 est non-conjugé
    Application
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogène
    RHBDD1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RHBDD1.
    Isotype
    IgG
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    Discover our top product RHBDD1 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    Autre désignation
    RHBDD1 (RHBDD1 Produits)
    Synonymes
    anticorps MGC84665, anticorps RRP4, anticorps 4930418P06Rik, anticorps mRHBDD1, anticorps RGD1306477, anticorps rRHBDD1, anticorps rhomboid domain containing 1, anticorps rhomboid domain containing 1 L homeolog, anticorps RHBDD1, anticorps rhbdd1.L, anticorps rhbdd1, anticorps Rhbdd1
    Sujet
    The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.Synonyms: HSD-50, HSD50, Rhomboid domain-containing protein 1
    ID gène
    84236
    UniProt
    Q8TEB9
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