RHBDD2
Reactivité: Humain, Souris, Rat
ELISA, WB, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA. Western blot: 1 - 2 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Ferretti, Canzoneri, Barbeito, Croce, Abba, Lacunza: "Spatiotemporal expression of Rhomboid domain containing 2 (Rhbdd2) during rat development." dans: Acta histochemica, Vol. 117, Issue 7, pp. 635-41, (2016) (PubMed).
Canzoneri, Lacunza, Isla Larrain, Croce, Abba: "Rhomboid family gene expression profiling in breast normal tissue and tumor samples." dans: Tumour biology, Vol. 35, Issue 2, pp. 1451-8, (2014) (PubMed).
The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. Little is known about the role of RHBDD2. Its overexpression in breast carcinoma appears to be an indicator of poor prognosis and may play a role in breast cancer progression. The related proteins RHBDD1 and RHBDD3 are both involved in the regulation of apoptosis, suggesting that RHBDD2 may also be involved in the modulation of apoptotic activity.Synonyms: RHBDL7, Rhomboid domain-containing protein 2