RIMS3 anticorps (N-Term)

N° du produit ABIN500610

Détail du produit anti-RIMS3 anticorps

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIMS3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Rim3 at N-term. It is predicted to have no cross-reactivity to other Rim proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: Rim3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur RIMS3

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Autre désignation: RIMS3 (RIMS3 Produits)

Synonymes: anticorps NIM3, anticorps RIM3, anticorps Nim2, anticorps Nim3, anticorps A730060M23Rik, anticorps Rim3, anticorps mKIAA0237, anticorps RIMS3, anticorps MGC145981, anticorps si:ch211-239d6.1, anticorps regulating synaptic membrane exocytosis 3, anticorps RIMS3, anticorps Rims3, anticorps rims3

Sujet: Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.Synonyms: KIAA0237, Nim3, RIM 3, RIM3 gamma, Rab-3-interacting molecule 3, Regulating synaptic membrane exocytosis protein 3

ID gène: 9783

NCBI Accession: NP_055562

UniProt: Q9UJD0

Pathways: Stem Cell Maintenance, Synaptic Vesicle Exocytosis