MEX3D anticorps (Center)

N° du produit ABIN500616

Détail du produit anti-MEX3D anticorps

Antigène: MEX3D (Mex-3 Homolog D (MEX3D))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Rkhd1.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: Rkhd1 antibody was raised against a 15 amino acid peptide from near the center of human Rkhd1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MEX3D

Antigène: MEX3D (Mex-3 Homolog D (MEX3D))

Autre désignation: MEX3D / RKHD1 (MEX3D Produits)

Synonymes: anticorps RKHD1, anticorps MEX3D, anticorps rkhd1, anticorps mex3, anticorps tino, anticorps rnf193, anticorps ok/sw-cl.4, anticorps MEX-3D, anticorps MEX3, anticorps OK/SW-cl.4, anticorps RNF193, anticorps TINO, anticorps BC059858, anticorps Rkhd1, anticorps mex-3 RNA binding family member D, anticorps mex-3 RNA binding family member D L homeolog, anticorps mex3 RNA binding family member D, anticorps MEX3D, anticorps mex3d.L, anticorps mex3d, anticorps Mex3d

Sujet: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: KIAA2031, RING finger and KH domain-containing protein 1, RING finger protein 193, RNA-binding protein MEX3D, RNF193, TINO

ID gène: 399664

UniProt: Q86XN8