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RSPO1 anticorps (N-Term)

RSPO1 Reactivité: Humain, Rat, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500638
  • Antigène Voir toutes RSPO1 Anticorps
    RSPO1 (R-Spondin 1 (RSPO1))
    Épitope
    • 15
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 38
    • 33
    • 15
    • 15
    • 15
    • 15
    • 15
    Humain, Rat, Souris
    Hôte
    • 46
    • 6
    • 1
    Lapin
    Clonalité
    • 47
    • 6
    Polyclonal
    Conjugué
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp RSPO1 est non-conjugé
    Application
    • 36
    • 15
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects RSPO1. It will not cross-react with RSPO family members.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    RSPO1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human RSPO1.
    Isotype
    IgG
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    Discover our top product RSPO1 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    RSPO1 (R-Spondin 1 (RSPO1))
    Autre désignation
    RSPO1 (RSPO1 Produits)
    Synonymes
    anticorps RGD1565558, anticorps CRISTIN3, anticorps RSPO, anticorps R-spondin, anticorps Rspondin, anticorps wu:fj81e05, anticorps zgc:92153, anticorps R-spondin 1, anticorps Rspo1, anticorps RSPO1, anticorps LOC100049655, anticorps rspo1
    Sujet
    RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular b-catenin, thereby regulating functions mediated by b-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.Synonyms: R-spondin-1, Roof plate-specific spondin-1
    ID gène
    284654
    NCBI Accession
    NP_001033722
    UniProt
    Q2MKA7
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