DLGAP2
Reactivité: Humain, Rat
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 594
Indications d'application
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Antigène
DLGAP2
(Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
anticorps PSD-95, anticorps DAP2, anticorps SAPAP2, anticorps 6430596N04Rik, anticorps Sapap2, anticorps DLG associated protein 2, anticorps disks large-associated protein 2, anticorps discs, large (Drosophila) homolog-associated protein 2a, anticorps discs, large (Drosophila) homolog-associated protein 2, anticorps DLGAP2, anticorps LOC463960, anticorps dlgap2a, anticorps LOC100447448, anticorps Dlgap2
Sujet
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP2 are known to exist.Synonyms: DAP-2, DAP2, Disks large-associated protein 2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2