SCO2 anticorps (C-Term)

N° du produit ABIN500688

Détail du produit anti-SCO2 anticorps

Antigène: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCO2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SCO2.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: SCO2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human SCO2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur SCO2

Antigène: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Autre désignation: SCO2 (SCO2 Produits)

Synonymes: anticorps CEMCOX1, anticorps MYP6, anticorps SCO1L, anticorps SCO cytochrome oxidase deficient homolog 2 (yeast), anticorps SCO2 cytochrome c oxidase assembly protein, anticorps SCO2, cytochrome c oxidase assembly protein, anticorps SCO2, anticorps Sco2

Sujet: Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.Synonyms: Synthesis of cytochrome c oxidase 2, cytochrome oxidase deficient homolog 2

ID gène: 3184203

UniProt: O43819, Q5KW01

Pathways: Transition Metal Ion Homeostasis, L'effet Warburg