SLITRK1 anticorps (C-Term)

N° du produit ABIN500750

Détail du produit anti-SLITRK1 anticorps

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Épitope: C-Term

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLITRK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SLITRK1 at C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.

Réactivité croisée (Details): Species reactivity (tested):Huamn, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Slitrk1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur SLITRK1

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Autre désignation: SLITRK1 (SLITRK1 Produits)

Synonymes: anticorps DKFZp459G0529, anticorps LRRC12, anticorps TTM, anticorps 3200001I04Rik, anticorps SLIT and NTRK like family member 1, anticorps SLIT and NTRK-like family, member 1, anticorps SLITRK1, anticorps slitrk1, anticorps Slitrk1

Sujet: SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.Synonyms: KIAA1910, LRRC12, Leucine-rich repeat-containing protein 12, SLIT and NTRK-like protein 1

ID gène: 114798

NCBI Accession: NP_443142

UniProt: Q96PX8