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SLC51B anticorps (AbBy Fluor® 680)

OSTBETA Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal AbBy Fluor® 680
N° du produit ABIN5008063
  • Antigène Voir toutes SLC51B (OSTBETA) Anticorps
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC51B est conjugé à/à la AbBy Fluor® 680
    Application
    • 18
    • 7
    • 3
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OST-beta
    Isotype
    IgG
    Top Product
    Discover our top product OSTBETA Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    Autre désignation
    OST-beta (OSTBETA Produits)
    Synonymes
    anticorps Ostb, anticorps Ostbeta, anticorps RGD1565748, anticorps OSTB, anticorps OSTBETA, anticorps solute carrier family 51, beta subunit, anticorps solute carrier family 51 beta subunit, anticorps Slc51b, anticorps SLC51B
    Sujet

    Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.

    Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

    ID gène
    123264
    Pathways
    Regulation of Carbohydrate Metabolic Process
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