SRPX anticorps (N-Term)
-
- Antigène Voir toutes SRPX Anticorps
- SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SRPX est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogène
- SRPX1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human SRPX1.
- Isotype
- IgG
- Top Product
- Discover our top product SRPX Anticorps primaire
-
-
- Indications d'application
-
ELISA. Western blot: 0.25 - 0.5 μg/mL. Immunhistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
-
- Antigène
- SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))
- Autre désignation
- SRPX / ETX1 (SRPX Produits)
- Synonymes
- anticorps DRS, anticorps ETX1, anticorps SRPX1, anticorps drs, anticorps drs-1, anticorps drs-2, anticorps mDRS-1, anticorps mDRS-2, anticorps Drs, anticorps sushi repeat containing protein, X-linked, anticorps sushi-repeat-containing protein, anticorps sushi-repeat-containing protein, X-linked, anticorps SRPX, anticorps Srpx
- Sujet
- SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.Synonyms: Sushi repeat-containing protein SRPX
- ID gène
- 8406
- NCBI Accession
- NP_006298
-