OTOA anticorps (AA 231-330) (AbBy Fluor® 680)
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- Antigène Voir toutes OTOA Anticorps
- OTOA (Otoancorin (OTOA))
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Épitope
- AA 231-330
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OTOA est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human OTOA/DFNB22
- Isotype
- IgG
- Top Product
- Discover our top product OTOA Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- OTOA (Otoancorin (OTOA))
- Autre désignation
- OTOA/DFNB22 (OTOA Produits)
- Synonymes
- anticorps CT108, anticorps DFNB22, anticorps RGD1562741, anticorps otoancorin, anticorps otoancorin L homeolog, anticorps OTOA, anticorps otoa.L, anticorps otoa, anticorps Otoa
- Sujet
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Synonyms: Cancer/testis antigen 108, CT108, Deafness, autosomal recessive 22, DFNB22, OTOA, OTOAN_HUMAN, Otoancorin.
Background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
- ID gène
- 146183
- UniProt
- Q7RTW8
- Pathways
- Sensory Perception of Sound
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