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OTOA anticorps (AA 231-330) (AbBy Fluor® 750)

OTOA Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 750
N° du produit ABIN5008078
  • Antigène Voir toutes OTOA Anticorps
    OTOA (Otoancorin (OTOA))
    Épitope
    • 14
    • 8
    • 8
    • 7
    • 1
    AA 231-330
    Reactivité
    • 29
    • 4
    Souris
    Hôte
    • 29
    • 1
    Lapin
    Clonalité
    • 29
    • 1
    Polyclonal
    Conjugué
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OTOA est conjugé à/à la AbBy Fluor® 750
    Application
    • 30
    • 16
    • 13
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human OTOA/DFNB22
    Isotype
    IgG
    Top Product
    Discover our top product OTOA Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OTOA (Otoancorin (OTOA))
    Autre désignation
    OTOA/DFNB22 (OTOA Produits)
    Synonymes
    anticorps CT108, anticorps DFNB22, anticorps RGD1562741, anticorps otoancorin, anticorps otoancorin L homeolog, anticorps OTOA, anticorps otoa.L, anticorps otoa, anticorps Otoa
    Sujet

    Synonyms: Cancer/testis antigen 108, CT108, Deafness, autosomal recessive 22, DFNB22, OTOA, OTOAN_HUMAN, Otoancorin.

    Background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

    ID gène
    146183
    UniProt
    Q7RTW8
    Pathways
    Sensory Perception of Sound
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