IL1RL1 anticorps (N-Term)

N° du produit ABIN500811

Détail du produit anti-IL1RL1 anticorps

Antigène: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1RL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ST2 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Peptide Affinity Chromatography

Immunogène: A synthetic peptide corresponding to 16 amino acids at the amino-terminus of Mouse ST2. Remarks: This peptide is common to all three known ST2 isoforms.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Positive Control: Mouse Kidney Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL1RL1

Antigène: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Autre désignation: IL1RL1 / ST2 (IL1RL1 Produits)

Synonymes: anticorps DER4, anticorps Fit-1, anticorps Ly84, anticorps ST2L, anticorps St2, anticorps St2-rs1, anticorps T1, anticorps T1/ST2, anticorps FIT-1, anticorps IL33R, anticorps ST2, anticorps ST2V, anticorps FIT1, anticorps interleukin 1 receptor-like 1, anticorps interleukin 1 receptor like 1, anticorps Il1rl1, anticorps IL1RL1

Sujet: ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF (3). More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance (4,5). It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP (6).Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623

ID gène: 9173

NCBI Accession: NP_003847