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SYPL2 anticorps (C-Term)

SYPL2 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500857
  • Antigène Voir toutes SYPL2 Anticorps
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    Épitope
    C-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 1
    Lapin
    Clonalité
    • 1
    Polyclonal
    Conjugué
    • 1
    Cet anticorp SYPL2 est non-conjugé
    Application
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects SYPL2. It will not cross-react with SYPL1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    SYPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SYPL.
    Isotype
    IgG
  • Indications d'application
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    Autre désignation
    SYPL2 (SYPL2 Produits)
    Synonymes
    anticorps AI552439, anticorps Mg29, anticorps MG29, anticorps mg29, anticorps MGC88982, anticorps Sypl, anticorps fc22a07, anticorps wu:fc22a07, anticorps zgc:110355, anticorps sypl, anticorps wu:fd54d09, anticorps zgc:65838, anticorps synaptophysin-like 2, anticorps synaptophysin like 2, anticorps synaptophysin like 2 S homeolog, anticorps synaptophysin-like 2b, anticorps synaptophysin-like 2a, anticorps Sypl2, anticorps SYPL2, anticorps sypl2.S, anticorps sypl2, anticorps sypl2b, anticorps sypl2a
    Sujet
    SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. At least two isoforms of SYPL2 are known to exist.Synonyms: Synaptophysin-like protein 2
    ID gène
    284612
    NCBI Accession
    NP_001035799
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