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CD248 anticorps (C-Term)

CD248 Reactivité: Humain, Souris, Rat WB, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500885
  • Antigène Voir toutes CD248 Anticorps
    CD248 (CD248 Molecule, Endosialin (CD248))
    Épitope
    • 16
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 40
    • 30
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 36
    • 5
    • 1
    Lapin
    Clonalité
    • 38
    • 4
    Polyclonal
    Conjugué
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD248 est non-conjugé
    Application
    • 40
    • 19
    • 15
    • 13
    • 13
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    This antibody detects CD248 / TEM1 at C-term. It recognizes both isoforms.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Peptide affinity chromatography
    Immunogène
    TEM1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human TEM1.
    Isotype
    IgG
    Top Product
    Discover our top product CD248 Anticorps primaire
  • Indications d'application
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD248 (CD248 Molecule, Endosialin (CD248))
    Autre désignation
    CD248 / TEM1 (CD248 Produits)
    Synonymes
    anticorps CD164L1, anticorps TEM1, anticorps 2610111G01Rik, anticorps AI842296, anticorps Cd164l1, anticorps Tem1, anticorps fb96b12, anticorps wu:fb96b12, anticorps zgc:162651, anticorps CD248 molecule, anticorps CD248 antigen, endosialin, anticorps CD248 molecule, endosialin a, anticorps CD248, anticorps Cd248, anticorps cd248a
    Sujet
    Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion. At least two isoforms of TEM1 are known to exist.Synonyms: CD164L1, Endosialin, Tumor endothelial marker 1
    ID gène
    57124
    NCBI Accession
    NP_065137
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