PRKACG anticorps (AA 251-351) (AbBy Fluor® 750)
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- Antigène Voir toutes PRKACG Anticorps
- PRKACG (Protein Kinase, CAMP-Dependent, Catalytic, gamma (PRKACG))
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Épitope
- AA 251-351
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRKACG est conjugé à/à la AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PKA gamma
- Isotype
- IgG
- Top Product
- Discover our top product PRKACG Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PRKACG (Protein Kinase, CAMP-Dependent, Catalytic, gamma (PRKACG))
- Autre désignation
- PKA gamma (PRKACG Produits)
- Synonymes
- anticorps KAPG, anticorps PKACg, anticorps PRKACG, anticorps protein kinase cAMP-activated catalytic subunit gamma, anticorps PRKACG
- Sujet
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Synonyms: KAPG, PKA C gamma, PRKACG, Protein kinase cAMP dependent catalytic gamma, Serine threonine protein kinase, KAPCG_HUMAN.
Background: PKA (or cAPK) is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, C beta, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states. C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.
- ID gène
- 5568
- Pathways
- AMPK Signaling, Signalisation Hedgehog, Thyroid Hormone Synthesis, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism
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