RASD2 anticorps (N-Term)

N° du produit ABIN500891

Détail du produit anti-RASD2 anticorps

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects RASD2 / TEM2 at N-term. TEM2 antibody may cross-react with the closely related protein RASD1.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: TEM2 antibody was raised against a 16 amino acid peptide near the amino terminus of the human TEM2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur RASD2

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Autre désignation: RASD2 / TEM2 (RASD2 Produits)

Synonymes: anticorps RASD2, anticorps MGC:4834, anticorps Rhes, anticorps TEM2, anticorps 4930526B11Rik, anticorps AU045414, anticorps TEM-2, anticorps RASD family member 2, anticorps RASD family, member 2, anticorps RASD2, anticorps Rasd2

Sujet: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.Synonyms: GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2

ID gène: 23551

UniProt: Q96D21