GPR124 anticorps (C-Term)

N° du produit ABIN500895

Détail du produit anti-GPR124 anticorps

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR124 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects GPR124 / TEM5 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, rat

Purification: Peptide affinity chromatography

Immunogène: TEM5 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human TEM5.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur GPR124

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Autre désignation: GPR124 / TEM5 (GPR124 Produits)

Synonymes: anticorps TEM5, anticorps 8430414O08Rik, anticorps 9530074E10Rik, anticorps Tem5, anticorps mKIAA1531, anticorps MGC69043, anticorps si:dkey-208c22.2, anticorps GPR124, anticorps adhesion G protein-coupled receptor A2, anticorps adhesion G protein-coupled receptor A2 L homeolog, anticorps G-protein coupled receptor 124, anticorps ADGRA2, anticorps Adgra2, anticorps adgra2.L, anticorps adgra2, anticorps LOC616111

Sujet: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.Synonyms: G-protein coupled receptor 124, KIAA1531, Tumor endothelial marker 5

ID gène: 25960

UniProt: Q96PE1