TLR8 anticorps (Middle Region)

N° du produit ABIN500964

Détail du produit anti-TLR8 anticorps

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Épitope: Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody detects CD288 / TLR8 at center.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Peptide affinity chromatography

Immunogène: TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: CD288 / TLR8 (TLR8 Produits)

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). Like TLR7, TLR8 is localized to endosomal or lysosomal compartments (6) and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA (7). Human but not murine TLR8 confers responsiveness to the antiviral compound R-848 (8).Synonyms: Toll-like receptor 8, UNQ249/PRO286

ID gène: 51311

NCBI Accession: NP_619542

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades