KCNK18 anticorps (Center)

N° du produit ABIN501034

Détail du produit anti-KCNK18 anticorps

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur KCNK18

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Autre désignation: KCNK18 (KCNK18 Produits)

Synonymes: anticorps K2p18.1, anticorps MGR13, anticorps TRESK, anticorps TRESK-2, anticorps TRESK2, anticorps TRIK, anticorps Gm781, anticorps Tresk, anticorps Tresk-2, anticorps Trik, anticorps potassium two pore domain channel subfamily K member 18, anticorps potassium channel, subfamily K, member 18, anticorps KCNK18, anticorps Kcnk18

Sujet: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.Synonyms: KCNK18, Potassium channel subfamily K member 18, TRESK, TRIK, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel

ID gène: 338567

NCBI Accession: NP_862823