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m1ip1 anticorps (AA 21-120) (AbBy Fluor® 680)

m1ip1 Reactivité: Humain, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 680
N° du produit ABIN5010596
  • Antigène Voir toutes m1ip1 Anticorps
    m1ip1 (Mid1-Interacting Protein 1 (m1ip1))
    Épitope
    • 14
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 43
    • 24
    • 10
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 39
    • 3
    • 1
    Lapin
    Clonalité
    • 42
    • 1
    Polyclonal
    Conjugué
    • 19
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp m1ip1 est conjugé à/à la AbBy Fluor® 680
    Application
    • 31
    • 12
    • 12
    • 12
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SLAP
    Isotype
    IgG
    Top Product
    Discover our top product m1ip1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    m1ip1 (Mid1-Interacting Protein 1 (m1ip1))
    Autre désignation
    SLAP (m1ip1 Produits)
    Synonymes
    anticorps MIG12, anticorps TB10, anticorps G12-like, anticorps S14R, anticorps STRAIT11499, anticorps THRSPL, anticorps 3110038L01Rik, anticorps Mig12, anticorps slap, anticorps mig12, anticorps thrspl, anticorps MGC80850, anticorps zgc:73223, anticorps g12, anticorps wu:fj32f05, anticorps thymosin beta 10, anticorps MID1 interacting protein 1, anticorps Mid1-interacting protein 1, anticorps Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)), anticorps MID1 interacting protein 1 S homeolog, anticorps MID1 interacting protein 1b, anticorps MID1 interacting protein 1a, anticorps TMSB10, anticorps MID1IP1, anticorps m1ip1, anticorps Mid1ip1, anticorps mid1ip1.S, anticorps mid1ip1b, anticorps mid1ip1a
    Sujet

    Synonyms: hSLAP, SLA 1, SLA, SLA1, SLAP 1, SLAP, SLAP-1, SLAP1, SLAP1_HUMAN, Src like adapter, Src like adapter protein 1, Src like adaptor, SRC-like-adapter, Src-like-adapter protein 1.

    Background: The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.

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