SLC22A17 anticorps (AA 475-538) (AbBy Fluor® 680)
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- Antigène Voir toutes SLC22A17 Anticorps
- SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
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Épitope
- AA 475-538
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC22A17 est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SLC22A17
- Isotype
- IgG
- Top Product
- Discover our top product SLC22A17 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
- Autre désignation
- Slc22A17 (SLC22A17 Produits)
- Synonymes
- anticorps 1700094C23Rik, anticorps 24p3R, anticorps AU041908, anticorps AW555662, anticorps BOIT, anticorps Boct, anticorps mBOCT, anticorps BOCT, anticorps NGALR, anticorps NGALR2, anticorps NGALR3, anticorps hBOIT, anticorps rBOCT, anticorps solute carrier family 22 member 17, anticorps solute carrier family 22 (organic cation transporter), member 17, anticorps solute carrier family 22, member 17, anticorps SLC22A17, anticorps Slc22a17
- Sujet
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Synonyms: BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3, Solute carrier family 22 member 17, 24p3 receptor, Brain-type organic cation transporter, Lipocalin-2 receptor, Neutrophil gelatinase-associated lipocalin receptor, SLC22A17
Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).
- ID gène
- 51310
- UniProt
- Q8WUG5
- Pathways
- Transition Metal Ion Homeostasis
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