SRI anticorps (AbBy Fluor® 750)

N° du produit ABIN5010846

Détail du produit anti-SRI anticorps (AbBy Fluor® 750)

Antigène: SRI (Sorcin (SRI))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRI est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SR1/Sorcin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SRI

Antigène: SRI (Sorcin (SRI))

Autre désignation: Sorcin (SRI Produits)

Synonymes: anticorps zgc:64070, anticorps sri, anticorps SRI, anticorps CP-22, anticorps CP22, anticorps SCN, anticorps V19, anticorps 2210417O06Rik, anticorps 2900070H08Rik, anticorps Sor, anticorps sorcin, anticorps Sorcin, anticorps sorcin L homeolog, anticorps sorcin S homeolog, anticorps SRI, anticorps sri, anticorps EDI_060410, anticorps EDI_160670, anticorps EDI_002860, anticorps EDI_076560, anticorps CpipJ_CPIJ004933, anticorps CpipJ_CPIJ008581, anticorps Tsp_05707, anticorps sri.L, anticorps sri.S, anticorps Sri

Sujet:

Synonyms: 22 kDa protein, Calcium binding protein amplied in mutlidrug resistant cells, CP 22, CP-22, CP22, SCN, Sorcin class 4 gene, Sorcin, SORCN_HUMAN, SRI, V19.

Background: Sorcin is a highly conserved protein, with 95 % homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin EF hand? motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.

ID gène: 6717

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity