SPO11 anticorps (AbBy Fluor® 750)
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- Antigène Voir toutes SPO11 Anticorps
- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPO11 est conjugé à/à la AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SPO11
- Isotype
- IgG
- Top Product
- Discover our top product SPO11 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
- Autre désignation
- SPO11 (SPO11 Produits)
- Synonymes
- anticorps CT35, anticorps SPATA43, anticorps TOPVIA, anticorps zgc:77876, anticorps AI449549, anticorps Meiotic recombination protein spo-11, anticorps SPO11, initiator of meiotic double stranded breaks, anticorps SPO11 meiotic protein covalently bound to DSB, anticorps spo-11, anticorps SPO11, anticorps Spo11, anticorps spo11
- Sujet
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Synonyms: Meiotic recombination protein SPO 11, Meiotic recombination protein SPO11, MGC39953, SPO 11, SPO11 meiotic protein covalently bound to DSB homolog, SPO11 meiotic protein covalently bound to DSB like, SPO11_HUMAN.
Background: Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
- ID gène
- 23626
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