UCMA anticorps (C-Term)
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- Antigène Voir toutes UCMA Anticorps
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
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Épitope
- C-Term
- Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UCMA est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects UCMA.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse
- Purification
- Affinity chromatography
- Immunogène
- UCMA antibody was raised against a 16 amino acid peptide near the carboxy terminus of human UCMA.
- Isotype
- IgG
- Top Product
- Discover our top product UCMA Anticorps primaire
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- Indications d'application
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ELISA. Western blot: 2.5 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
- Autre désignation
- UCMA (UCMA Produits)
- Synonymes
- anticorps BN, anticorps GRP-10, anticorps preproGRP, anticorps proGRP, anticorps grp, anticorps GRP2, anticorps ucma, anticorps zgc:162317, anticorps C10orf49, anticorps GRP, anticorps RGD1308977, anticorps 1110017I16Rik, anticorps AW121955, anticorps Grp, anticorps GRP1, anticorps zgc:85838, anticorps gastrin releasing peptide, anticorps upper zone of growth plate and cartilage matrix associated, anticorps upper zone of growth plate and cartilage matrix associated L homeolog, anticorps upper zone of growth plate and cartilage matrix associated a, anticorps upper zone of growth plate and cartilage matrix associated b, anticorps GRP, anticorps UCMA, anticorps ucma.L, anticorps ucmaa, anticorps ucma, anticorps Ucma, anticorps ucmab
- Sujet
- UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes. It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias. UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature. UCMA is processed by a furin-like protease into two fragments, an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C). Application of recombinant UCMA-C to primary osteoblasts, mesenchymal stem cells, and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation, but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation, suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells. At least two isoforms of UCMA are known to exist.Synonyms: C10orf49, Unique cartilage matrix-associated protein
- ID gène
- 221044
- NCBI Accession
- NP_660357
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