HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) anticorps (AbBy Fluor® 750)
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- Antigène Voir toutes HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Anticorps
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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Épitope
- AA 331-430
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Syncytin-2
- Isotype
- IgG
- Top Product
- Discover our top product Herv-frd Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
- Autre désignation
- Syncytin 2 (Herv-frd Produits)
- Synonymes
- anticorps ERVFRDE1, anticorps GLLL6191, anticorps HERV-FRD, anticorps HERV-W/FRD, anticorps UNQ6191, anticorps envFRD, anticorps Gm52, anticorps Syna, anticorps endogenous retrovirus group FRD member 1, envelope, anticorps ERVFRD-1, anticorps Ervfrd-1
- Classe de substances
- Viral Protein
- Sujet
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Synonyms: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, ERVFRD-1, UNQ6191/PRO20218
Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732). Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).
- ID gène
- 405754
- UniProt
- P60508
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