DAPK3
Reactivité: Souris, Rat
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA. Western blot: 1: 500 to 1: 1000. An approximate 40 kDa band can be detected, whichrepresents the pro-enzyme of DNase II. Immunflourescence. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
anticorps DAPK3, anticorps dapk3, anticorps wu:fc25b08, anticorps si:dkey-57k2.5, anticorps MGC114871, anticorps ZIP, anticorps ZIPK, anticorps dlk, anticorps Dapkl, anticorps death associated protein kinase 3, anticorps death-associated protein kinase 3, anticorps death-associated protein kinase 3 L homeolog, anticorps DAPK3, anticorps dapk3, anticorps dapk3.L, anticorps Dapk3
Sujet
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .Synonyms: DAP kinase 3, DAP-like kinase, DLK, Death-associated protein kinase 3, ZIP-kinase