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TMEM59 anticorps (AA 141-240) (AbBy Fluor® 680)

TMEM59 Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 680
N° du produit ABIN5011722
  • Antigène Voir toutes TMEM59 Anticorps
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Épitope
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reactivité
    • 14
    • 11
    Souris
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TMEM59 est conjugé à/à la AbBy Fluor® 680
    Application
    • 21
    • 12
    • 12
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TMEM59
    Isotype
    IgG
    Top Product
    Discover our top product TMEM59 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Autre désignation
    TMEM59 (TMEM59 Produits)
    Synonymes
    anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59
    Sujet

    Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, TMEM59, TMEM59 transmembrane protein 59, TMM59_HUMAN, Transmembrane protein 59.

    Background: TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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