Tppp anticorps (AA 61-150) (AbBy Fluor® 750)

N° du produit ABIN5011838

Détail du produit anti-Tppp anticorps (AbBy Fluor® 750)

Antigène: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Épitope: AA 61-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tppp est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TPPP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Tppp

Antigène: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Autre désignation: TPPP (Tppp Produits)

Synonymes: anticorps TPPP/p25, anticorps TPPP1, anticorps p24, anticorps p25, anticorps p25alpha, anticorps 2900041A09Rik, anticorps AI849835, anticorps RGD1310121, anticorps tubulin polymerization promoting protein, anticorps TPPP, anticorps Tppp

Sujet:

Synonyms: Tubulin Polymerization Promoting Protein 24, 25 kDa brain specic protein, 25 kDa brain-specic protein, Brain specic protein p25 alpha, Glycogen synthase kinase 3 GSK3 inhibitor p24, p24, p25, p25-alpha, p25alpha, TPPP, TPPP/p25, TPPP_HUMAN, TPPP1, Tubulin polymerization promoting protein, Tubulin polymerization-promoting protein.

Background: Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome.