UBE2E2 anticorps (AA 1-100) (AbBy Fluor® 750)

N° du produit ABIN5012153

Détail du produit anti-UBE2E2 anticorps (AbBy Fluor® 750)

Antigène: UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))

Épitope: AA 1-100

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2E2 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UBE2E2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur UBE2E2

Antigène: UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))

Autre désignation: UBE2E2 (UBE2E2 Produits)

Synonymes: anticorps ubch8, anticorps UBCH8, anticorps wu:fb38h07, anticorps zgc:92467, anticorps BC016265, anticorps ubiquitin-conjugating enzyme E2E 2, anticorps ubiquitin conjugating enzyme E2E 2 L homeolog, anticorps ubiquitin conjugating enzyme E2E 2, anticorps Ube2e2 protein, anticorps ubiquitin conjugating enzyme E2 E2, anticorps UBE2E2, anticorps ube2e2.L, anticorps ube2e2, anticorps Ube2e2

Sujet:

Synonyms: UB2E2_HUMAN, UBC4/5 homolog yeast, UBCH 8, UbcH8, Ube2e2, Ubiquitin carrier protein E2, Ubiquitin conjugating enzyme E2 E2, Ubiquitin conjugating enzyme E2E 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2E 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2E 2, Ubiquitin protein ligase E2, Ubiquitin-conjugating enzyme E2 E2, Ubiquitin-protein ligase E2.

Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.

ID gène: 7325