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RAX anticorps (AA 100-313)

RAX Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5027505
  • Antigène Voir toutes RAX Anticorps
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Épitope
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 100-313
    Reactivité
    • 17
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 12
    • 5
    Lapin
    Clonalité
    • 12
    • 5
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    Cet anticorp RAX est non-conjugé
    Application
    • 15
    • 8
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Purification
    Protein A Chromatography
    Immunogène
    A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.
    Isotype
    IgG
    Top Product
    Discover our top product RAX Anticorps primaire
  • Indications d'application
    WB: 1-2 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Antigène
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Autre désignation
    RAX (RAX Produits)
    Sujet
    RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
    Poids moléculaire
    30 kDa
    ID gène
    8575
    UniProt
    O75569
    Pathways
    Regulatory RNA Pathways
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