RAX anticorps (AA 100-313)

N° du produit ABIN5027505

Détail du produit anti-RAX anticorps

Antigène: RAX (Retina and Anterior Neural Fold Homeobox (RAX))

Épitope: AA 100-313

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAX est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur RAX

Antigène: RAX (Retina and Anterior Neural Fold Homeobox (RAX))

Autre désignation: RAX (RAX Produits)

Sujet: RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.

Poids moléculaire: 30 kDa

ID gène: 8575

UniProt: O75569

Pathways: Regulatory RNA Pathways