SPIB anticorps (AA 50-260)
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- Antigène Voir toutes SPIB Anticorps
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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Épitope
- AA 50-260
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPIB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Protein A Chromatography
- Immunogène
- A partial length recombinant Spi-B protein (amino acids 50-260) was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product SPIB Anticorps primaire
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- Indications d'application
- WB: 2-4 μg/mL, IHC: 5 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Antigène
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
- Autre désignation
- Spi-B (SPIB Produits)
- Synonymes
- anticorps spi-b, anticorps spib, anticorps spiba, anticorps SPI-B, anticorps B42b-like, anticorps Spi-B, anticorps Spi-B transcription factor L homeolog, anticorps Spi-B transcription factor, anticorps Spi-B transcription factor (Spi-1/PU.1 related), anticorps spib.L, anticorps SPIB, anticorps Spib
- Sujet
- Spi-B belongs to the ETS family transcription containing a conserved ETS domain which specifically binds to a purine-rich DNA sequence called the PU-box (5'-GAGGAA-3'). Spi-B has two known isoforms (28 and 18 kDa) localized in nucleus and cytoplasm. Spi-B contains two transactivation domains (TAD) at the N- terminal end which may be required for transcriptional activation of the target genes. Spi-B is involved in development of plasmacytoid dendritic cells (natural interferon producing cells) and B-cell development. Spi-B acts as a lymphoid specific enhancer. Spi-B is highly expressed in plasmacytoid dendritic cells (pDCs), B-cells and stem cell populations of the liver.
- Poids moléculaire
- 28 kDa
- ID gène
- 6689
- UniProt
- Q01892
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