UNC93B1 anticorps (AA 300-597)

N° du produit ABIN5027623

Détail du produit anti-UNC93B1 anticorps

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Épitope: AA 300-597

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC93B1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 4-6 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur UNC93B1

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Autre désignation: UNC93B (UNC93B1 Produits)

Synonymes: anticorps UNC93, anticorps IIAE1, anticorps UNC93B, anticorps Unc-93B1, anticorps Unc93b, anticorps unc-93 homolog B1, TLR signaling regulator, anticorps unc-93 homolog B1 (C. elegans), anticorps UNC93B1, anticorps Unc93b1

Sujet: Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.

Poids moléculaire: 70 kDa

ID gène: 81622

UniProt: Q9H1C4

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades