ATG4A anticorps (AA 102-113) (FITC)

N° du produit ABIN5065987

Détail du produit anti-ATG4A anticorps (FITC)

Antigène: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Épitope: AA 102-113

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4A est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.,Detects ~45 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Peptide Affinity Purified

Immunogène: Synthetic peptide from the mid-protein of Human ATG4A (aa. 102-113)

Isotype: IgG

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:1000 dilution of ABIN5065987 was sufficient for detection of ATG4A in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur ATG4A

Antigène: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Autre désignation: ATG4A (ATG4A Produits)

Synonymes: anticorps apg4a, anticorps autl2, anticorps F6E13.27, anticorps APG4A, anticorps zgc:111958, anticorps Aut2a, anticorps AUTL2, anticorps AI627006, anticorps AV169859, anticorps Apg4a, anticorps Atg4al, anticorps Autl2, anticorps Atg4a, anticorps autophagy related 4A cysteine peptidase L homeolog, anticorps autophagy related 4A cysteine peptidase, anticorps Peptidase family C54 protein, anticorps ATG4 autophagy related 4 homolog A (S. cerevisiae), anticorps autophagy related 4A, cysteine peptidase, anticorps atg4a.L, anticorps ATG4A, anticorps AT2G44140, anticorps atg4a, anticorps Atg4a

Sujet: Autophagy related 4A, cysteine peptidase (ATG4A or APG4A) is a C-54 cysteine protease that also belongs to the family of autophagin proteins, and is primarily found in skeletal muscle and brain. ATG4A is involved in cellular autophagy and has been studied as a target for cancer therapy. Specifically it cleaves GATE-16. Mutations in the ATG4a gene is critical for redox regulation and inhibits autophagosome formation.

ID gène: 115201

NCBI Accession: NP_001308216

UniProt: Q8WYN0

Pathways: Autophagy