ULK1 anticorps (AA 567-577) (Atto 488)

N° du produit ABIN5066139

Détail du produit anti-ULK1 anticorps (Atto 488)

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Épitope: AA 567-577

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK1 est conjugé à/à la Atto 488

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,Detects ~100 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Peptide Affinity Purified

Immunogène: Synthetic peptide from the mid-protein of Human ULK1 (aa. 567-577)

Isotype: IgG

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:1000 dilution of ABIN5066139 was sufficient for detection of ULK1 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur ULK1

Antigène: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Autre désignation: ULK1 (ULK1 Produits)

Synonymes: anticorps ATG1, anticorps ATG1A, anticorps UNC51, anticorps Unc51.1, anticorps hATG1, anticorps si:dkey-11o18.7, anticorps ulk1, anticorps ULK1, anticorps AU041434, anticorps mKIAA0722, anticorps zgc:195008, anticorps unc-51 like autophagy activating kinase 1, anticorps unc-51 like kinase 1, anticorps unc-51 like autophagy activating kinase 1a, anticorps ULK1, anticorps Ulk1, anticorps ulk1b, anticorps ulk1a

Sujet: UNC-51 like kinase 1 (ULK1) is widely expresed and contains an amino-terminal kinase domain followed by a central proline-serine rich domain and a highly conserved carboxy-terminal domain. It has been linked to axon growth and is essential for autophagy. Structurally, ULK1 is similar to ATG1, and it appears that both Atg1/ULK1 can bind to several ATG proteins regulating phosphorylation states and protein trafficking.

ID gène: 8408

NCBI Accession: NP_003556

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy