WDR45 anticorps (AA 312-322) (Atto 488)

N° du produit ABIN5066247

Détail du produit anti-WDR45 anticorps (Atto 488)

Antigène: WDR45 (WD Repeat Domain 45 (WDR45))

Épitope: AA 312-322

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR45 est conjugé à/à la Atto 488

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.,Detects ~40 kDa.

Réactivité croisée: Humain, Rat

Purification: Peptide Affinity Purified

Immunogène: Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)

Isotype: IgG

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:1000 dilution of ABIN5066247 was sufficient for detection of WIPI4 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur WDR45

Antigène: WDR45 (WD Repeat Domain 45 (WDR45))

Autre désignation: WDR45 (WDR45 Produits)

Synonymes: anticorps MGC80694, anticorps NBIA4, anticorps NBIA5, anticorps WDRX1, anticorps WIPI-4, anticorps WIPI4, anticorps C79260, anticorps DXImx38e, anticorps JM5, anticorps Sfc19, anticorps Wdrx1, anticorps zgc:56345, anticorps zgc:77017, anticorps WD repeat domain 45 S homeolog, anticorps WD repeat domain 45, anticorps wdr45.S, anticorps WDR45, anticorps Wdr45, anticorps wdr45

Sujet: WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.

ID gène: 11152

NCBI Accession: NP_001025067

UniProt: Q9Y484