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GDNF anticorps (Biotin)

GDNF Reactivité: Humain WB, IHC, ICC, IF Hôte: Lapin Polyclonal Biotin
N° du produit ABIN5066760
  • Antigène Voir toutes GDNF Anticorps
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Reactivité
    • 83
    • 42
    • 32
    • 16
    • 16
    • 1
    Humain
    Hôte
    • 78
    • 6
    • 3
    • 3
    Lapin
    Clonalité
    • 76
    • 13
    • 1
    Polyclonal
    Conjugué
    • 40
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDNF est conjugé à/à la Biotin
    Application
    • 74
    • 27
    • 25
    • 19
    • 16
    • 13
    • 13
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.,Detects ~24 kDa.
     Réactivité croisée
    Humain, Rat
    Purification
    Peptide Affinity Purified
    Immunogène
    Synthetic peptide from the mid-protein of Human GDNF
    Isotype
    IgG
    Top Product
    Discover our top product GDNF Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:1000 dilution of ABIN5066760 was sufficient for detection of GDNF in 15 μg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Autre désignation
    GDNF (GDNF Produits)
    Synonymes
    anticorps gdnf, anticorps GDNF, anticorps AI385739, anticorps gdnfa, anticorps hfb1-gdnf, anticorps ATF1, anticorps ATF2, anticorps HFB1-GDNF, anticorps HSCR3, anticorps glial cell derived neurotrophic factor, anticorps glial cell derived neurotrophic factor a, anticorps glial cell line derived neurotrophic factor, anticorps glial cell derived neurotrophic factor L homeolog, anticorps Gdnf, anticorps gdnfa, anticorps GDNF, anticorps gdnf.L
    ID gène
    2668
    NCBI Accession
    NP_000505
    UniProt
    P39905
    Pathways
    Signalisation RTK, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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