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FNIP1 anticorps (Atto 390)

FNIP1 Reactivité: Humain WB, IHC, IF, ICC Hôte: Lapin Polyclonal Atto 390
N° du produit ABIN5066840
  • Antigène Voir toutes FNIP1 Anticorps
    FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
    Reactivité
    • 18
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FNIP1 est conjugé à/à la Atto 390
    Application
    • 12
    • 11
    • 11
    • 10
    • 6
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung. Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue.,Detects ~130 kDa.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Peptide Affinity Purified
    Immunogène
    Synthetic peptide from the mid-protein of Human FNIP1
    Isotype
    IgG
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    A 1:1000 dilution of ABIN5066840 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
    Autre désignation
    FNIP1 (FNIP1 Produits)
    Synonymes
    anticorps FNIP1, anticorps DKFZp468P0310, anticorps A730024A03Rik, anticorps AI838773, anticorps AW557298, anticorps folliculin interacting protein 1, anticorps FNIP1, anticorps fnip1, anticorps Fnip1
    Sujet
    Folliculin-interacting protein 1 (FNIP1) is a co-chaperone of HSP90 (1). It Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways and may regulate the phosphorylation of RPS6KB1 (2). FNIP1 is strongly expressed in the heart, liver placenta, muscle, nasal mucosa, salivary gland, and uvula. Elevated levels of FNIP1 have been detected in renal cell carcinoma (RCC) (3).
    ID gène
    96459
    NCBI Accession
    NP_001008738
    UniProt
    Q8TF40
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